DE LA SALLE UNIVERSITY 
College of Science
            Department of Biology

LBYBIOE – Fundamentals of Genetic Laboratory
Prerequisites:  
_____________________________________________________________________________________														    Instructor   :  ______________________________    Contact details :  ________________________
Instructor:______________________________    Contactdetails :  ________________________
Consultation Hours: ______________________    Class Schedule and Room: ________________

Course Description	
A course that deals with exercises on chromosomal basis of inheritance, structure of genetic material and Mendelian and Non-Mendelian inheritance.

Learning Outcomes	
On completion of this course, the student is expected to present the following learning outcomes in line with the Expected Lasallian Graduate Attributes (ELGA).
ELGA	Learning Outcome	
Critical and Creative Thinker
Effective Communicator
Lifelong Learner
Service-Driven Citizen	On completion of the course, students are expected to be able to demonstrate proficiency of basic techniques in genetics and be able to directly apply its relevance to the existing needs and problems of the society.

Final Course Output	
As evidence of attaining the above learning outcome, the student is required to complete the following during the indicated dates of the term.
Learning Outcome	Required Output	Due Date	
Students will demonstrate proficiency of basic techniques and tools which can be employed in classical transmission (Mendelian) genetics, as well as demonstrate some of the techniques used in modern genetics laboratories, including using bioinformatics in the elucidation of gene identity and function. Students will demonstrate improved critical thinking and data analysis, as well as the ability to work in groups, through preparation of pre-lab exercises, laboratory reports and worksheets; they will demonstrate individual achievement of the genetic concepts and data analysis through written laboratory tests.
	Scientific Papers
Submission of pre-lab exercises and full paper after every exercise.		
	Field Trip
This is a required activity for LBYBIOE. Its main objective is to expose students to the actual applications of genetic techniques in research facilities and service institutions (IRRI, St. Luke’s Research and Biotechnology Division, NIH-UP Manila. 
The field trip does not only entail exposure but will also engage  students’ critical thinking and analysis.	Week 8	
	Reflection Paper
Submission of a reflection paper based from the field trip.	Week 9	

Rubric for assessment	
The following are the Rubrics that will serve as the basis for assessing the performance of the students on their preparations and presentation of the required final output for the course.

A.  Reflection Papers

Criteria	Experts!
(3.5-4.0)	Team Players
(2.5-5.4)	Laid-Back
(1.5-2.4)	Spacemen
(1.0-1.4)	

Organization
(40%)	Information is very organized with well-constructed paragraphs, use of subheadings, and information is factual and correct. 	Information is organized with well-constructed paragraphs and information is factual and correct.	Information is organized but paragraphs are not well constructed and information is factual.	Information appears not only disorganized but inaccurate.

Quality of Information
(40%)	Information clearly relates to the main topic.  It includes several supporting details and/or examples	Information clearly relates to the main topic.  It provides 1 – 2 supporting details and/or examples 	Information has little to do with the main topic. No details and/or examples are given	Information has nothing to do with the main topic

Multimedia
(20%)	No grammatical, spelling or punctuation errors	Almost no grammatical, spelling, or punctuation errors	A few grammatical, spelling, or punctuation errors	Many grammatical, spelling, or punctuation errors

Additional Requirements	
•	•	Active participation in class discussions
•	•	Performance of laboratory activities
•	•	Attendance and participation in laboratory exercises
•	•	Timely submission of activity worksheet, reflection papers and assignments which are non-plagiarized
•	•	Passing long exams
       Others: post-lab discussion, cooperative learning, web-based and laboratory activities

Grading Systems	
    Laboratory reports                                                  30%
    Field trip/ Seminar (whichever is arranged)         15%
    Long Exams                                                             50%
    Attendance/Participation                                       5%
    TOTAL                                                                  100%
     Passing Mark                                                         60%	Scale:
            92-100%           4.0
            86-  91              3.5
            80-  85               3.0
            75-  79%            2.5
            70-  74%            2.0
            65-  69%            1.5
            60-  64%            1.0
               <60%	          0.0	

Learning Plan	

Learning Outcome	Laboratory Topic	Week	Learning Activities	
Students will demonstrate proficiency of basic techniques and tools, as well as demonstrate some of the techniques used in modern genetics laboratories. Students will demonstrate improved critical thinking and data analysis based on written laboratory reports and tests.	Overview and Introduction	1	Group dynamics	
	DNA Extraction 	2-3	Group dynamics	
	Polymerase Chain Reaction (PCR)	4-5	Group dynamics	
	DNA Sequencing and Data Analysis (Computer Lab: M314)	6	Group dynamics	
	1st Laboratory Assessment	7		
	Field Trip	8	Group dynamics	
	Binomial Expansion	9	Reflection Paper
	
	Chi-Square Test: Goodness of Fit	10	Group dynamics	
	Quantitative Genetics	11	Group dynamics	
	Population Genetics	12	Group dynamics	
	Final Examination	13		

References	

Klug, WS and Cummings, MR. 2001. Essential of Genetics. 4th Ed. 
Grffiths, A and Luvontin, R. 2000. An Introduction to Genetic Analysis. 7th Ed. 

Text/Materials: Laboratory exercises developed by the Biology Department.

Online Resources	
http:// www.ncbi.nlm.nih.gov/ OMIM
The Board of Regents of the University of Wisconsin System. (2007). Available at http://www.biotech.wisc.edu/Education/Poster/backmaster.html “Biotechnology: tools for genetic ingenuity
http://casgroup.fiu.edu/writingcenter/
 
Class Policies	
•	Honesty and integrity are integral components of the academic process.
•	Absence and tardiness are strongly discouraged.
•	Attentiveness and active participation are critical to successful learning.
	The use of mobile phones and other electronic devices is not allowed during class hours, unless   necessary or upon the teacher’s approval. 
•	The policies on academic dishonesty, attendance, and behavior stipulated in your Student Handbook are honored in this course. 
•	No make up for missed exams.
•	Any kind of plagiarism is strongly prohibited.

Approved by

Dr. Mary Jane C. Flores
Chair, Biology Department